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Concept information

... > Genetic Phenomena > Genetic Structures > Genome > Genome Components > Genes > Genes, Neoplasm > Genes, Tumor Suppressor > Genes, BRCA2
Genetic Phenomena > Inheritance Patterns > Genes, Recessive > Genes, Tumor Suppressor > Genes, BRCA2
... > Genetic Phenomena > Genetic Structures > Genome > Genome Components > Genes > Genes, Recessive > Genes, Tumor Suppressor > Genes, BRCA2

Terme préférentiel

Genes, BRCA2  

Type

  • mesh:Descriptor

Définition

  • A tumor suppressor gene (GENES, TUMOR SUPPRESSOR) located on human chromosome 13 at locus 13q12.3. Mutations in this gene predispose humans to breast and ovarian cancer. It encodes a large, nuclear protein that is an essential component of DNA repair pathways, suppressing the formation of gross chromosomal rearrangements. (from Genes Dev 2000;14(11):1400-6)

Concept générique

Concepts associés

Synonyme(s)

  • BRCA2 Gene

Qualificatif(s) autorisé(s)

Traductions

URI

http://data.loterre.fr/ark:/67375/JVR-GXSXX0C7-K

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RDF/XML TURTLE JSON-LD Date de création 25/07/2001, dernière modification le 08/07/2008