Concept information
Terme préférentiel
Pre-B Cell Receptors
Type
-
mesh:Descriptor
Définition
- Membrane proteins in precursor B-LYMPHOCYTES (pre-B Cells). They are composed of membrane-bound MU IMMUNOGLOBULIN HEAVY CHAINS in complex with SURROGATE LIGHT CHAINS instead of conventional IMMUNOGLOBULIN LIGHT CHAINS. Only successful rearrangement of the VDJ segments, at the Ig heavy chain gene locus (IMMUNOGLOBULIN HEAVY CHAIN GENES), will generate mu heavy chains that can pair with surrogate light chains. Thus formation of the pre-B cell receptors is an important checkpoint in the development of mature B cells.
Concept générique
Concepts spécifiques
Synonyme(s)
- Pre-B Cell Receptor
Qualificatif(s) autorisé(s)
- administration & dosage (Qualifier)
- agonists (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- biosynthesis (Qualifier)
- blood (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- deficiency (Qualifier)
- drug effects (Qualifier)
- genetics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- physiology (Qualifier)
- radiation effects (Qualifier)
- therapeutic use (Qualifier)
- ultrastructure (Qualifier)
Traductions
-
français
-
pré-BCR
-
préBCR
-
Récepteurs des cellules pré-B
-
Récepteurs des précurseurs des cellules B
-
Récepteurs des précurseurs des lymphocytes B
URI
http://data.loterre.fr/ark:/67375/JVR-H4Q8LTGW-H
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