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Concept information

Terme préférentiel

Pyroglobulins  

Type

  • mesh:Descriptor

Définition

  • Atypical gamma immunoglobulins characterized by their irreversible heat denaturation at 56-degrees C. Pyroprecipitation is inhibited at pH below 3 and above 9. The presence of pyroglobulins in the serum is the cause of pyroglobulinemia. They are frequently present in multiple myeloma and the pyroglobulin precipitate binds complement, reacts with rheumatoid factor, produces passive cutaneous anaphylaxis, generalized passive anaphylaxis and passive Arthus-type phenomena.

Concept générique

Action(s) pharmacologique(s)

Traductions

URI

http://data.loterre.fr/ark:/67375/JVR-H7PVTXT1-D

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RDF/XML TURTLE JSON-LD Date de création 01/08/1975, dernière modification le 30/06/2005