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Concept information

Terme préférentiel

Prion Proteins  

Type

  • mesh:Descriptor

Définition

  • Membrane glycosylphosphatidylinositol-anchored glycoproteins that may aggregate into rod-like structures. The prion protein (PRNP) gene is characterized by five TANDEM REPEAT SEQUENCES that encode a highly unstable protein region of five octapeptide repeats. Mutations in the repeat region and elsewhere in this gene are associated with CREUTZFELDT-JAKOB DISEASE; FATAL FAMILIAL INSOMNIA; GERSTMANN-STRAUSSLER DISEASE; Huntington disease-like 1, and KURU. An overlapping open reading frame within the PRNP gene that encodes a protein which is smaller and structurally unrelated to major prion protein.

Concept générique

Concepts spécifiques

Synonyme(s)

  • CD230 Antigen
  • Creutzfeldt-Jakob Disease Protein
  • Fatal Familial Insomnia Protein
  • Major Prion Protein
  • Prion Protein
  • PrP Proteins

Traductions

  • français

  • Antigène CD230
  • CD230
  • Protéine de l'insomnie fatale familiale
  • Protéine de la maladie de Creutzfeldt-Jakob
  • Protéine du prion
  • Protéine majeure du prion
  • Protéine prion
  • Protéines du prion
  • Protéines PrP

URI

http://data.loterre.fr/ark:/67375/JVR-HCKK0D73-1

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RDF/XML TURTLE JSON-LD Date de création 08/07/2016, dernière modification le 24/05/2017