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Concept information

Amino Acids, Peptides, and Proteins > Proteins > DNA-Binding Proteins > Repressor Proteins > Zinc Finger Protein Gli3
Amino Acids, Peptides, and Proteins > Proteins > Transcription Factors > Repressor Proteins > Zinc Finger Protein Gli3
Amino Acids, Peptides, and Proteins > Proteins > DNA-Binding Proteins > Kruppel-Like Transcription Factors > Zinc Finger Protein Gli3
Amino Acids, Peptides, and Proteins > Proteins > Transcription Factors > Kruppel-Like Transcription Factors > Zinc Finger Protein Gli3

Terme préférentiel

Zinc Finger Protein Gli3  

Type

  • mesh:Descriptor

Définition

  • A zinc finger transcription factor that contains five CYS2-HIS2 ZINC FINGERS and binds to the GLI consensus sequence 5'-GGGTGGTC-3'. The full-length protein functions as a transcriptional activator whereas the truncated C-terminal form functions as a transcriptional repressor of the Sonic Hedgehog (Shh) signaling pathway; a balance between these two forms is critical for limb and digit development. GLI3 also plays a critical role in the differentiation and proliferation of CHONDROCYTES.

Concept générique

Synonyme(s)

  • GLI-Kruppel Family Member 3 Protein
  • Glioma-Associated Oncogene Family Zinc Finger 3 Protein

Qualificatif(s) autorisé(s)

Traductions

  • Protéine à doigts de zinc Gli3

    français

  • Membre-3 de la famille des protéines GLI-Kruppel
  • Protéine à doigt de zinc Gli3
  • Protéine-3 à doigts de zinc de la famille des oncogènes associés au gliome

URI

http://data.loterre.fr/ark:/67375/JVR-HCM74R92-Z

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RDF/XML TURTLE JSON-LD Date de création 11/07/2017, dernière modification le 27/02/2017