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Concept information

... > Genetic Phenomena > Genetic Structures > Genome > Genome Components > Genes > Genes, Neoplasm > Oncogenes > Proto-Oncogenes > Genes, myc

Terme préférentiel

Genes, myc  

Type

  • mesh:Descriptor

Définition

  • Family of retrovirus-associated DNA sequences (myc) originally isolated from an avian myelocytomatosis virus. The proto-oncogene myc (c-myc) codes for a nuclear protein which is involved in nucleic acid metabolism and in mediating the cellular response to growth factors. Truncation of the first exon, which appears to regulate c-myc expression, is crucial for tumorigenicity. The human c-myc gene is located at 8q24 on the long arm of chromosome 8.

Concept générique

Concepts associés

Synonyme(s)

  • myc Genes

Qualificatif(s) autorisé(s)

Traductions

URI

http://data.loterre.fr/ark:/67375/JVR-HD9PT452-N

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RDF/XML TURTLE JSON-LD Date de création 28/06/1990, dernière modification le 08/07/2008