Concept information
Terme préférentiel
Folic Acid Antagonists
Type
-
mesh:Descriptor
Définition
- Inhibitors of the enzyme, dihydrofolate reductase (TETRAHYDROFOLATE DEHYDROGENASE), which converts dihydrofolate (FH2) to tetrahydrofolate (FH4). They are frequently used in cancer chemotherapy. (From AMA, Drug Evaluations Annual, 1994, p2033)
Concept générique
Synonyme(s)
- Antifolate
- Antifolates
- Dihydrofolate Reductase Inhibitor
- Dihydrofolate Reductase Inhibitors
- Folic Acid Antagonist
Qualificatif(s) autorisé(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- analysis (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- economics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- urine (Qualifier)
Traductions
-
français
-
Antagonistes de l'acide folique
-
Anti-folates
-
Anti-foliques
-
Antifolates
URI
http://data.loterre.fr/ark:/67375/JVR-HMPWGQQZ-2
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