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... > Chemical Actions and Uses > Pharmacologic Actions > Molecular Mechanisms of Pharmacological Action > Neurotransmitter Agents > Histamine Agents > Histamine Antagonists > Histamine H1 Antagonists > Histamine H1 Antagonists, Non-Sedating
... > Chemical Actions and Uses > Pharmacologic Actions > Physiological Effects of Drugs > Neurotransmitter Agents > Histamine Agents > Histamine Antagonists > Histamine H1 Antagonists > Histamine H1 Antagonists, Non-Sedating

Terme préférentiel

Histamine H1 Antagonists, Non-Sedating  

Type

  • mesh:Descriptor

Définition

  • A class of non-sedating drugs that bind to but do not activate histamine receptors (DRUG INVERSE AGONISM), thereby blocking the actions of histamine or histamine agonists. These antihistamines represent a heterogenous group of compounds with differing chemical structures, adverse effects, distribution, and metabolism. Compared to the early (first generation) antihistamines, these non-sedating antihistamines have greater receptor specificity, lower penetration of BLOOD-BRAIN BARRIER, and are less likely to cause drowsiness or psychomotor impairment. Active enantiomers and selective derivatives of second generation H1 antagonists.

Concept générique

Concepts associés

Synonyme(s)

  • H1 Antihistamines, Non-Sedating
  • Second Generation Antihistamine
  • Second Generation Antihistamines
  • Second Generation H1 Antagonist
  • Second Generation H1 Antagonists

Qualificatif(s) autorisé(s)

Traductions

  • Antihistaminiques H1 non sédatifs

    français

  • Antagonistes de l'histamine H1 non sédatifs
  • Anti-histaminiques de seconde génération
  • Anti-histaminiques H1 non sédatifs
  • Antihistaminiques de seconde génération

URI

http://data.loterre.fr/ark:/67375/JVR-J57SG0C2-6

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RDF/XML TURTLE JSON-LD Date de création 02/07/2002, dernière modification le 27/05/2020