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Concept information

... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Membrane Transport Proteins > Solute Carrier Proteins > Sodium-Potassium-Chloride Symporters > Solute Carrier Family 12, Member 1
... > Amino Acids, Peptides, and Proteins > Proteins > Carrier Proteins > Membrane Transport Proteins > Solute Carrier Proteins > Sodium-Potassium-Chloride Symporters > Solute Carrier Family 12, Member 1
... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Membrane Transport Proteins > Ion Pumps > Symporters > Sodium-Potassium-Chloride Symporters > Solute Carrier Family 12, Member 1
... > Amino Acids, Peptides, and Proteins > Proteins > Carrier Proteins > Membrane Transport Proteins > Ion Pumps > Symporters > Sodium-Potassium-Chloride Symporters > Solute Carrier Family 12, Member 1

Terme préférentiel

Solute Carrier Family 12, Member 1  

Type

  • mesh:Descriptor

Définition

  • Na-K-Cl transporter in the ASCENDING LIMB OF LOOP OF HENLE. It mediates active reabsorption of sodium chloride and is inhibited by LOOP DIURETICS such as FUROSEMIDE; and BUMETANIDE. Mutations in the gene encoding SLC12A1 are associated with a BARTTER SYNDROME.

Concept générique

Concepts associés

Synonyme(s)

  • BSC1 Transport Protein
  • Bumetanide-Sensitive Sodium-(Potassium)-Chloride Cotransporter 2
  • Kidney-Specific Na-K-Cl Symporter
  • NKCC2 Cotransporter
  • NKCC2 Protein
  • SLC12A1 Cotransporter
  • SLC12A1 Protein

Qualificatif(s) autorisé(s)

Traductions

  • Membre-1 de la famille-12 des transporteurs de solutés

    français

  • Cotransporteur NKCC2
  • Cotransporteur SLC12A1
  • Cotransporteur-2 de sodium-(potassium)-chlore sensible au bumétanide
  • Protéine de transport BSC1
  • Protéine NKCC2
  • Protéine SLC12A1
  • Symporteur Na-K-Cl spécifique du rein

URI

http://data.loterre.fr/ark:/67375/JVR-JD7WP4L1-D

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RDF/XML TURTLE JSON-LD Date de création 08/07/2013, dernière modification le 24/11/2015