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Concept information

Macromolecular Substances > Multiprotein Complexes > Mitochondrial Permeability Transition Pore
Amino Acids, Peptides, and Proteins > Proteins > Mitochondrial Proteins > Mitochondrial Membrane Transport Proteins > Mitochondrial Permeability Transition Pore
... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Membrane Transport Proteins > Mitochondrial Membrane Transport Proteins > Mitochondrial Permeability Transition Pore
... > Amino Acids, Peptides, and Proteins > Proteins > Carrier Proteins > Membrane Transport Proteins > Mitochondrial Membrane Transport Proteins > Mitochondrial Permeability Transition Pore

Terme préférentiel

Mitochondrial Permeability Transition Pore  

Type

  • mesh:Descriptor

Définition

  • A multiprotein inner mitochondrial complex which opens only under certain pathological conditions (e.g., OXIDATIVE STRESS) uncoupling the membrane leading to APOPTOSIS and MITOCHONDRIAL TRANSMEMBRANE PERMEABILITY-DRIVEN NECROSIS particularly in CARDIOMYOCYTES during MYOCARDIAL REPERFUSION INJURY.

Concept générique

Synonyme(s)

  • Mitochondrial Megachannel
  • Mitochondrial Permeability Transition Pore (mPTP)
  • mPTP Protein

Qualificatif(s) autorisé(s)

Traductions

URI

http://data.loterre.fr/ark:/67375/JVR-JNBD52V9-5

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RDF/XML TURTLE JSON-LD Date de création 07/07/2020, dernière modification le 21/02/2020