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Concept information

... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Receptors, Cell Surface > Receptors, Immunologic > Platelet Membrane Glycoproteins > Platelet Glycoprotein GPIIb-IIIa Complex
... > Amino Acids, Peptides, and Proteins > Proteins > Glycoproteins > Membrane Glycoproteins > Platelet Membrane Glycoproteins > Platelet Glycoprotein GPIIb-IIIa Complex
... > Carbohydrates > Glycoconjugates > Glycoproteins > Membrane Glycoproteins > Platelet Membrane Glycoproteins > Platelet Glycoprotein GPIIb-IIIa Complex
... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Membrane Glycoproteins > Platelet Membrane Glycoproteins > Platelet Glycoprotein GPIIb-IIIa Complex
... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Receptors, Cell Surface > Receptors, Immunologic > Integrins > Receptors, Cytoadhesin > Platelet Glycoprotein GPIIb-IIIa Complex

Terme préférentiel

Platelet Glycoprotein GPIIb-IIIa Complex  

Type

  • mesh:Descriptor

Définition

  • Platelet membrane glycoprotein complex important for platelet adhesion and aggregation. It is an integrin complex containing INTEGRIN ALPHAIIB and INTEGRIN BETA3 which recognizes the arginine-glycine-aspartic acid (RGD) sequence present on several adhesive proteins. As such, it is a receptor for FIBRINOGEN; VON WILLEBRAND FACTOR; FIBRONECTIN; VITRONECTIN; and THROMBOSPONDINS. A deficiency of GPIIb-IIIa results in GLANZMANN THROMBASTHENIA.

Concept générique

Concepts associés

Synonyme(s)

  • Glycoproteins IIb-IIIa
  • GPIIb-IIIa Receptors
  • Integrin alpha-IIb beta-3
  • Integrin alphaIIbbeta3

Qualificatif(s) autorisé(s)

Traductions

URI

http://data.loterre.fr/ark:/67375/JVR-JR0GSG99-7

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RDF/XML TURTLE JSON-LD Date de création 26/05/1995, dernière modification le 09/07/2013