: MeSH: Ubiquitin-Protein Ligase Complexes

Enzymes and Coenzymes > Enzymes > Ligases > Ubiquitin-Protein Ligase Complexes

Ubiquitin-Protein Ligase Complexes

Complexes of enzymes that catalyze the covalent attachment of UBIQUITIN to other proteins by forming a peptide bond between the C-terminal GLYCINE of UBIQUITIN and the alpha-amino groups of LYSINE residues in the protein. The complexes play an important role in mediating the selective-degradation of short-lived and abnormal proteins. The complex of enzymes can be broken down into three components that involve activation of ubiquitin (UBIQUITIN-ACTIVATING ENZYMES), conjugation of ubiquitin to the ligase complex (UBIQUITIN-CONJUGATING ENZYMES), and ligation of ubiquitin to the substrate protein (UBIQUITIN-PROTEIN LIGASES).

http://data.loterre.fr/ark:/67375/JVR-K58LPDJM-S

RDF/XML TURTLE JSON-LD Date de création 09/07/2003, dernière modification le 02/06/2016

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