Concept information
Terme préférentiel
Mechlorethamine
Type
-
mesh:Descriptor
Définition
- A biologic alkylating agent that exerts its cytotoxic effects by forming DNA ADDUCTS and DNA interstrand crosslinks, thereby inhibiting rapidly proliferating cells. The hydrochloride is an antineoplastic agent used to treat HODGKIN DISEASE and LYMPHOMA.
Concept générique
Synonyme(s)
- 126-85-2 (N-oxide)
- 302-70-5 (N-oxide, HCl)
- 50D9XSG0VR
- 51-75-2
- 55-86-7 (HCl)
- Bis(2-chloroethyl)methylamine
- Chlorethazine
- Chlormethine
- Ethanamine, 2-chloro-N-(2-chloroethyl)-N-methyl-
- L0MR697HHI
- Methylchlorethamine
- Mustine
- Nitrogen Mustard
Qualificatif(s) autorisé(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- agonists (Qualifier)
- analogs & derivatives (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- economics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- urine (Qualifier)
Action(s) pharmacologique(s)
Traductions
-
français
-
126-85-2 (N-oxide)
-
302-70-5 (N-oxide, HCl)
-
50D9XSG0VR
-
51-75-2
-
55-86-7 (HCl)
-
Ethanamine, 2-chloro-N-(2-chloroethyl)-N-methyl-
-
L0MR697HHI
URI
http://data.loterre.fr/ark:/67375/JVR-KBLWNJWG-6
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