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Concept information

Immune System Diseases > Mast Cell Activation Disorders

Terme préférentiel

Mast Cell Activation Disorders  

Type

  • mesh:Descriptor

Définition

  • A spectrum of primary, secondary, and idiopathic disorders involving MAST CELLS and characterized by an aberrant release of mast cell mediators which result in multiple and variable inflammatory and allergic symptoms. These disorders are associated with various mutations in tyrosine kinase KIT (PROTO-ONCOGENE PROTEINS C-KIT) and other genes, underlying conditions, and responses to allergic or non-allergic triggers of mast cell stimulation and degranulation such as local anesthetics, lactam antibiotics, muscle relaxants, specific foods, environmental toxins, physical conditions such as vibration, cold, pressure, and stress.

Concept générique

Synonyme(s)

  • Mast Cell Activation Disease
  • Mast Cell Disease
  • Mast-Cell Disease

Traductions

URI

http://data.loterre.fr/ark:/67375/JVR-KHBHJ973-G

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RDF/XML TURTLE JSON-LD Date de création 09/07/2021, dernière modification le 07/07/2021