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Concept information

Terme préférentiel

Glomerulonephritis, Membranoproliferative  

Type

  • mesh:Descriptor

Définition

  • Chronic glomerulonephritis characterized histologically by proliferation of MESANGIAL CELLS, increase in the MESANGIAL EXTRACELLULAR MATRIX, and a thickening of the glomerular capillary walls. This may appear as a primary disorder or secondary to other diseases including infections and autoimmune disease SYSTEMIC LUPUS ERYTHEMATOSUS. Various subtypes are classified by their abnormal ultrastructures and immune deposits. Hypocomplementemia is a characteristic feature of all types of MPGN. A type of mesangiocapillary glomerulonephritis that is characterized by immune deposits on the endothelial side of the GLOMERULAR BASEMENT MEMBRANE leading to splitting and reduplication of the basement membrane. A type of mesangiocapillary glomerulonephritis that is characterized by the dark bands of electron-dense deposits in the GLOMERULAR BASEMENT MEMBRANE caused by autoantibodies against ALTERNATIVE PATHWAY C3 CONVERTASE (C3bBb). A type of mesangiocapillary glomerulonephritis that is characterized by subepithelial immune deposit and may be a variant of type I.

Synonyme(s)

  • Glomerulonephritis, Hypocomplementemic
  • Glomerulonephritis, Mesangiocapillary
  • Membranoproliferative Glomerulonephritis
  • Mesangiocapillary Glomerulonephritis
  • MPGN

Traductions

  • français

  • Glomérulonéphrite membrano-proliférative
  • Glomérulonéphrite mésangio-capillaire
  • Glomérulonéphrite mésangiocapillaire
  • GNMP
  • GNMP (GloméruloNéphrite MLembrano-Proliférative)

URI

http://data.loterre.fr/ark:/67375/JVR-KNF49J4P-Z

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RDF/XML TURTLE JSON-LD Date de création 08/06/1988, dernière modification le 30/06/2021