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Concept information

Amino Acids, Peptides, and Proteins > Proteins > Cell Cycle Proteins > F-Box-WD Repeat-Containing Protein 7
Amino Acids, Peptides, and Proteins > Proteins > Carrier Proteins > F-Box Proteins > F-Box-WD Repeat-Containing Protein 7
... > Enzymes and Coenzymes > Enzymes > Ligases > Ubiquitin-Protein Ligase Complexes > Ubiquitin-Protein Ligases > SKP Cullin F-Box Protein Ligases > F-Box-WD Repeat-Containing Protein 7

Terme préférentiel

F-Box-WD Repeat-Containing Protein 7  

Type

  • mesh:Descriptor

Définition

  • A component of SCF(FBW7) UBIQUITIN LIGASE that contains an F-box motif and multiple WD REPEATS. It recognizes and binds phosphorylated signals in several proteins involved in CELL PROLIFERATION and targets them to the SCF complex for UBIQUITINATION. Targets include CYCLIN E; PROTO-ONCOGENE PROTEINS C-JUN; PROTO-ONCOGENE PROTEINS C-MYC; and JNK MITOGEN-ACTIVATED PROTEIN KINASES.

Concept générique

Synonyme(s)

  • F-Box and WD-40 Domain-Containing Protein 7
  • FBXW7 Protein

Qualificatif(s) autorisé(s)

Traductions

URI

http://data.loterre.fr/ark:/67375/JVR-KQ1PJH0D-S

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RDF/XML TURTLE JSON-LD Date de création 11/07/2017, dernière modification le 27/02/2017