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Nutritional and Metabolic Diseases > Metabolic Diseases > Brain Diseases, Metabolic > Kernicterus
Nervous System Diseases > Central Nervous System Diseases > Brain Diseases > Brain Diseases, Metabolic > Kernicterus
Congenital, Hereditary, and Neonatal Diseases and Abnormalities > Infant, Newborn, Diseases > Erythroblastosis, Fetal > Kernicterus
Immune System Diseases > Erythroblastosis, Fetal > Kernicterus
Hemic and Lymphatic Diseases > Hematologic Diseases > Erythroblastosis, Fetal > Kernicterus
... > Urogenital Diseases > Female Urogenital Diseases and Pregnancy Complications > Pregnancy Complications > Fetal Diseases > Erythroblastosis, Fetal > Kernicterus
Congenital, Hereditary, and Neonatal Diseases and Abnormalities > Fetal Diseases > Erythroblastosis, Fetal > Kernicterus
Pathological Conditions, Signs and Symptoms > Pathologic Processes > Hyperbilirubinemia > Kernicterus

Terme préférentiel

Kernicterus  

Type

  • mesh:Descriptor

Définition

  • A term used pathologically to describe BILIRUBIN staining of the BASAL GANGLIA; BRAIN STEM; and CEREBELLUM and clinically to describe a syndrome associated with HYPERBILIRUBINEMIA. Clinical features include athetosis, MUSCLE SPASTICITY or hypotonia, impaired vertical gaze, and DEAFNESS. Nonconjugated bilirubin enters the brain and acts as a neurotoxin, often in association with conditions that impair the BLOOD-BRAIN BARRIER (e.g., SEPSIS). This condition occurs primarily in neonates (INFANT, NEWBORN), but may rarely occur in adults. (Menkes, Textbook of Child Neurology, 5th ed, p613)

Concept générique

Synonyme(s)

  • Bilirubin Encephalopathy
  • Encephalopathy, Bilirubin
  • Encephalopathy, Hyperbilirubinemic
  • Hyperbilirubinemic Encephalopathy

Qualificatif(s) autorisé(s)

Traductions

  • Ictère nucléaire

    français

  • Encéphalopathie bilirubinique
  • Encéphalopathie hyperbilirubinémique
  • Encéphalopathie par hyperbilirubinémie
  • Kernictère

URI

http://data.loterre.fr/ark:/67375/JVR-KR4JWLXF-Q

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RDF/XML TURTLE JSON-LD Date de création 01/01/1999, dernière modification le 09/07/2013