Passer au contenu principal

Medical Subject Headings (thesaurus)

Choisissez le vocabulaire dans lequel chercher

aligner
annoter
télécharger

Concept information

... > Enzymes and Coenzymes > Enzymes > Hydrolases > Esterases > Phosphoric Monoester Hydrolases > Phosphoinositide Phosphatases > Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases

Terme préférentiel

Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases  

Type

  • mesh:Descriptor

Définition

  • Phosphoinositide phosphatases that catalyze the dephosphorylation (hydrolysis) of phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P(3)) to produce PtdIns(3,4)P(2), which negatively regulates the PI3K ( 3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASES) pathways. They contain an SH2 DOMAIN and STERILE ALPHA MOTIF and have important functions in regulating the immune response and other cellular processes in vertebrates.

Concept générique

Synonyme(s)

  • SHIP Phosphatases
  • Src Homology 2 Domain-Containing Inositol Phosphatases

Qualificatif(s) autorisé(s)

Traductions

URI

http://data.loterre.fr/ark:/67375/JVR-KV7L8J51-C

Télécharger ce concept :

RDF/XML TURTLE JSON-LD Date de création 08/07/2016, dernière modification le 01/07/2016