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Concept information

Terme préférentiel

Lymphoma, Follicular  

Type

  • mesh:Descriptor

Définition

  • Malignant lymphoma in which the lymphomatous cells are clustered into identifiable nodules within the LYMPH NODES. The nodules resemble to some extent the GERMINAL CENTER of lymph node follicles and most likely represent neoplastic proliferation of lymph node-derived follicular center B-LYMPHOCYTES. A low-grade malignant lymphoma of follicular pattern in which there is no clear preponderance of one cell type (small or large) over another. The large cells, cleaved or noncleaved, are often 2-3 times larger in diameter than normal lymphocytes. A low-grade malignant lymphoma of predominantly follicular pattern. Follicles are of relatively uniform size and shape and the cells are usually somewhat larger than normal lymphocytes. Nuclei are irregular with prominent indentations and cytoplasm can rarely be identified. Cells exhibiting these characteristics are often called centrocytes. Malignant lymphoma in which the majority of neoplastic cells within the follicles are large cleaved or noncleaved cells. The degree to which the follicular center cells retain their ability to form follicles varies with the state of B-cell transformation.

Concept générique

Synonyme(s)

  • Brill-Symmers Disease
  • Follicular Lymphoma
  • Follicular Lymphoma, Giant
  • Giant Follicular Lymphoma
  • Lymphoma, Giant Follicular
  • Lymphoma, Nodular

Traductions

  • français

  • Lymphome folliculaire géant
  • Lymphome gigantofolliculaire
  • Lymphome nodulaire
  • Maladie de Brill-Symmers

URI

http://data.loterre.fr/ark:/67375/JVR-KW07963C-M

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RDF/XML TURTLE JSON-LD Date de création 01/01/1999, dernière modification le 10/05/2021