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Concept information

... > Eukaryota > Animals > Chordata > Vertebrates > Mammals > Eutheria > Rodentia > Muridae > Murinae > Mice > Mice, Mutant Strains > Mice, Inbred mdx
... > Eukaryota > Animals > Animal Population Groups > Animals, Laboratory > Animals, Inbred Strains > Mice, Inbred Strains > Mice, Inbred C57BL > Mice, Inbred mdx
... > Eukaryota > Animals > Chordata > Vertebrates > Mammals > Eutheria > Rodentia > Muridae > Murinae > Mice > Mice, Inbred Strains > Mice, Inbred C57BL > Mice, Inbred mdx

Terme préférentiel

Mice, Inbred mdx  

Type

  • mesh:Descriptor

Définition

  • A strain of mice arising from a spontaneous MUTATION (mdx) in inbred C57BL mice. This mutation is X chromosome-linked and produces viable homozygous animals that lack the muscle protein DYSTROPHIN, have high serum levels of muscle ENZYMES, and possess histological lesions similar to human MUSCULAR DYSTROPHY. The histological features, linkage, and map position of mdx make these mice a worthy animal model of DUCHENNE MUSCULAR DYSTROPHY.

Concept générique

Concepts associés

Synonyme(s)

  • Mice, mdx
  • Mouse, Inbred mdx
  • Mouse, mdx

Qualificatif(s) autorisé(s)

Traductions

URI

http://data.loterre.fr/ark:/67375/JVR-L9F1WM4N-6

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RDF/XML TURTLE JSON-LD Date de création 03/06/1993, dernière modification le 02/09/2020