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Concept information

Terme préférentiel

Myasthenic Syndromes, Congenital  

Type

  • mesh:Descriptor

Définition

  • A heterogeneous group of disorders characterized by a congenital defect in neuromuscular transmission at the NEUROMUSCULAR JUNCTION. This includes presynaptic, synaptic, and postsynaptic disorders (that are not of autoimmune origin). The majority of these diseases are caused by mutations of various subunits of the nicotinic acetylcholine receptor (RECEPTORS, NICOTINIC) on the postsynaptic surface of the junction. (From Arch Neurol 1999 Feb;56(2):163-7)

Synonyme(s)

  • Congenital Myasthenia
  • Congenital Myasthenia Gravis
  • Congenital Myasthenic Syndrome
  • Congenital Myasthenic Syndromes
  • Myasthenia Gravis, Congenital

Traductions

URI

http://data.loterre.fr/ark:/67375/JVR-LCCP1P97-K

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RDF/XML TURTLE JSON-LD Date de création 08/11/1999, dernière modification le 27/05/2020