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Concept information

Amino Acids, Peptides, and Proteins > Proteins > Nuclear Proteins > Mediator Complex
Amino Acids, Peptides, and Proteins > Peptides > Intracellular Signaling Peptides and Proteins > Adaptor Proteins, Signal Transducing > Mediator Complex
Amino Acids, Peptides, and Proteins > Proteins > Intracellular Signaling Peptides and Proteins > Adaptor Proteins, Signal Transducing > Mediator Complex
Amino Acids, Peptides, and Proteins > Proteins > Carrier Proteins > Adaptor Proteins, Signal Transducing > Mediator Complex
Macromolecular Substances > Multiprotein Complexes > Mediator Complex

Terme préférentiel

Mediator Complex  

Type

  • mesh:Descriptor

Définition

  • A large protein complex which acts as a signaling adaptor protein that allows communication between the various regulatory and functional components of GENETIC TRANSCRIPTION including DNA POLYMERASE II; GENERAL TRANSCRIPTION FACTORS; and TRANSCRIPTION FACTORS that are bound to upstream ENHANCER ELEMENTS. The mediator complex was originally studied in YEAST where at least 21 subunits were identified. Many of the yeast subunits are homologs to proteins in higher organisms that are found associated with specific nuclear receptors such as THYROID HORMONE RECEPTORS and VITAMIN D RECEPTORS.

Concept générique

Concepts spécifiques

Synonyme(s)

  • Mediator Transcription Complex

Qualificatif(s) autorisé(s)

Traductions

URI

http://data.loterre.fr/ark:/67375/JVR-LMFXKCX2-0

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RDF/XML TURTLE JSON-LD Date de création 06/07/2009, dernière modification le 30/03/2016