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Concept information

Immune System Phenomena > Complement Activation > Complement Pathway, Mannose-Binding Lectin

Terme préférentiel

Complement Pathway, Mannose-Binding Lectin  

Type

  • mesh:Descriptor

Définition

  • Complement activation triggered by the interaction of microbial POLYSACCHARIDES with serum MANNOSE-BINDING LECTIN resulting in the activation of MANNOSE-BINDING PROTEIN-ASSOCIATED SERINE PROTEASES. As in the classical pathway, MASPs cleave COMPLEMENT C4 and COMPLEMENT C2 to form C3 CONVERTASE (C4B2A) and the subsequent C5 CONVERTASE (C4B2A3B) leading to cleavage of COMPLEMENT C5 and assembly of COMPLEMENT MEMBRANE ATTACK COMPLEX.

Concept générique

Concepts associés

Synonyme(s)

  • Lectin-Complement Pathway
  • Mannan-Binding Lectin Complement Pathway
  • Mannan-Binding Lectin Pathway (Complement Activation)
  • Mannose-Binding Lectin Complement Pathway

Qualificatif(s) autorisé(s)

Traductions

  • Voie des lectines

    français

  • Voie d'activation par la lectine liant le mannose
  • Voie de la lectine
  • Voie de la MBL
  • Voie des lectines liant le mannose
  • Voie lectine liant le mannose

URI

http://data.loterre.fr/ark:/67375/JVR-LSV9J3JV-X

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RDF/XML TURTLE JSON-LD Date de création 03/07/2002, dernière modification le 23/06/2016