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Concept information

Terme préférentiel

Complement C3  

Type

  • mesh:Descriptor

Définition

  • A glycoprotein that is central in both the classical and the alternative pathway of COMPLEMENT ACTIVATION. C3 can be cleaved into COMPLEMENT C3A and COMPLEMENT C3B, spontaneously at low level or by C3 CONVERTASE at high level. The smaller fragment C3a is an ANAPHYLATOXIN and mediator of local inflammatory process. The larger fragment C3b binds with C3 convertase to form C5 convertase.

Concepts spécifiques

Synonyme(s)

  • C3 Complement
  • Complement 3
  • Complement Component 3

Action(s) pharmacologique(s)

Traductions

  • français

  • Composant C3 du complément
  • Facteur C3 du complément
  • Fraction C3 du complément
  • Protéine C3 du complément

URI

http://data.loterre.fr/ark:/67375/JVR-LZL6MQK8-S

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RDF/XML TURTLE JSON-LD Date de création 11/11/1974, dernière modification le 11/07/2005