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Concept information

... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Receptors, Cell Surface > Receptor Protein-Tyrosine Kinases > Receptor, trkA
... > Amino Acids, Peptides, and Proteins > Peptides > Intracellular Signaling Peptides and Proteins > Protein-Tyrosine Kinases > Receptor Protein-Tyrosine Kinases > Receptor, trkA
... > Amino Acids, Peptides, and Proteins > Proteins > Intracellular Signaling Peptides and Proteins > Protein-Tyrosine Kinases > Receptor Protein-Tyrosine Kinases > Receptor, trkA
... > Enzymes and Coenzymes > Enzymes > Transferases > Phosphotransferases > Phosphotransferases (Alcohol Group Acceptor) > Protein Kinases > Protein-Tyrosine Kinases > Receptor Protein-Tyrosine Kinases > Receptor, trkA
... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Receptors, Cell Surface > Receptors, Peptide > Receptors, Growth Factor > Receptors, Nerve Growth Factor > Receptor, trkA

Terme préférentiel

Receptor, trkA  

Type

  • mesh:Descriptor

Définition

  • A protein-tyrosine kinase receptor that is specific for NERVE GROWTH FACTOR; NEUROTROPHIN 3; neurotrophin 4, neurotrophin 5. It plays a crucial role in pain sensation and thermoregulation in humans. Gene mutations that cause loss of receptor function are associated with CONGENITAL INSENSITIVITY TO PAIN WITH ANHIDROSIS, while gene rearrangements that activate the protein-tyrosine kinase function are associated with tumorigenesis.

Concept générique

Synonyme(s)

  • c-trk Protein
  • gp140 c-trk
  • gp140(c-TRK)
  • Neurotrophic Tyrosine Kinase Receptor Type 1
  • NTRK1 Receptor
  • p140-trkA
  • Proto-Oncogene Products c-trk
  • Proto-Oncogene Protein trk
  • Receptor, Neurotrophic Tyrosine Kinase Type 1
  • trk1 Transforming Tryrosine Kinase
  • trkA Receptor
  • trk Proto-Oncogene Protein

Qualificatif(s) autorisé(s)

Traductions

  • Récepteur trkA

    français

  • Protéine proto-oncogène trk
  • Récepteur NTRK1
  • Récepteur tyrosine kinase neurotrophique type 1

URI

http://data.loterre.fr/ark:/67375/JVR-M0793Z0H-T

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RDF/XML TURTLE JSON-LD Date de création 04/11/1999, dernière modification le 21/05/2021