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Concept information

... > Heterocyclic Compounds > Heterocyclic Compounds, 1-Ring > Pyridines > Nicotinic Acids > Niacinamide > Sorafenib
Heterocyclic Compounds > Acids, Heterocyclic > Nicotinic Acids > Niacinamide > Sorafenib
... > Organic Chemicals > Hydrocarbons > Hydrocarbons, Cyclic > Hydrocarbons, Aromatic > Benzene Derivatives > Phenylurea Compounds > Sorafenib
Organic Chemicals > Amides > Urea > Phenylurea Compounds > Sorafenib

Terme préférentiel

Sorafenib  

Type

  • mesh:Descriptor

Définition

  • A niacinamide and phenylurea derivative that inhibits multiple intracellular and cell surface kinases thought to be involved in ANGIOGENESIS, including RAF KINASES and VEGF RECEPTORS. It is used in the treatment of advanced RENAL CELL CARCINOMA and HEPATOCELLULAR CARCINOMA, and for treatment of THYROID CARCINOMA refractory to radioactive iodine therapy.

Concept générique

Synonyme(s)

  • 2-Pyridinecarboxamide, 4-(4-((((4-chloro-3-(trifluoromethyl)phenyl)amino)carbonyl)amino)phenoxy)-N-methyl-
  • 5T62Q3B36J
  • 5XYK65KIGD
  • 9ZOQ3TZI87

Qualificatif(s) autorisé(s)

Action(s) pharmacologique(s)

Traductions

  • Sorafénib

    français

  • 2-Pyridinecarboxamide, 4-(4-((((4-chloro-3-(trifluoromethyl)phenyl)amino)carbonyl)amino)phenoxy)-N-methyl-
  • 5T62Q3B36J
  • 5XYK65KIGD
  • 9ZOQ3TZI87

URI

http://data.loterre.fr/ark:/67375/JVR-MBZ72W29-Q

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RDF/XML TURTLE JSON-LD Date de création 09/07/2018, dernière modification le 27/05/2020