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Concept information

Amino Acids, Peptides, and Proteins > Peptides > Intracellular Signaling Peptides and Proteins > Adaptor Proteins, Signal Transducing > Sequestosome-1 Protein
Amino Acids, Peptides, and Proteins > Proteins > Intracellular Signaling Peptides and Proteins > Adaptor Proteins, Signal Transducing > Sequestosome-1 Protein
Amino Acids, Peptides, and Proteins > Proteins > Carrier Proteins > Adaptor Proteins, Signal Transducing > Sequestosome-1 Protein
Amino Acids, Peptides, and Proteins > Proteins > Autophagy-Related Proteins > Sequestosome-1 Protein

Terme préférentiel

Sequestosome-1 Protein  

Type

  • mesh:Descriptor

Définition

  • A multidomain protein that is highly conserved among multicellular organisms. It contains a ZZ-type ZINC FINGER domain, C-terminal UBIQUITIN - associated (UBA) domain, and interacts with many other signaling proteins and enzymes including, atypical PROTEIN KINASE C; TNF RECEPTOR-ASSOCIATED FACTOR 6; subunits of the mTORC1 complex, and CASPASE-8. It functions in AUTOPHAGY as a receptor for the degradation of ubiquitinated substrates, and to co-ordinate signaling in response to OXIDATIVE STRESS.

Concept générique

Synonyme(s)

  • EBI3-Associated Protein of 60 KDa
  • EBIAP Protein
  • Phosphotyrosine-Independent Ligand For The Lck SH2 Domain Of 62 Kda
  • Ubiquitin-Binding Protein p62

Qualificatif(s) autorisé(s)

Traductions

  • Séquestosome-1

    français

  • Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 Kda
  • Protéine de 60 kDa associée à EBI3
  • Protéine EBIAP
  • Protéine p62 de liaison à l'ubiquitine
  • Protéine p62 fixant l'ubiquitine
  • Protéine p62 liant l'ubiquitine
  • Protéine séquestosome-1

URI

http://data.loterre.fr/ark:/67375/JVR-MCG7KKW6-T

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RDF/XML TURTLE JSON-LD Date de création 08/07/2016, dernière modification le 15/04/2016