Concept information
Terme préférentiel
Genes, rel
Type
-
mesh:Descriptor
Définition
- Family of retrovirus-associated DNA sequences (v-rel) originally isolated from an avian reticuloendotheliosis virus strain. The proto-oncogene rel (c-rel) codes for a subcellular (nuclear and cytoplasmic) transcription factor that has a role in lymphocyte differentiation. Translocation or overexpression of c-rel or competition from v-rel causes oncogenesis. The human rel gene is located at 2p12-13 on the short arm of chromosome 2.
Concept générique
Synonyme(s)
- rel Genes
Qualificatif(s) autorisé(s)
Traductions
-
français
-
Gène rel
URI
http://data.loterre.fr/ark:/67375/JVR-MFL64BSS-R
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