Concept information
...
DNA-Binding Proteins
Basic Helix-Loop-Helix Transcription Factors
Basic Helix-Loop-Helix Leucine Zipper Transcription Factors
Sterol Regulatory Element Binding Proteins
...
Transcription Factors
Basic Helix-Loop-Helix Transcription Factors
Basic Helix-Loop-Helix Leucine Zipper Transcription Factors
Sterol Regulatory Element Binding Proteins
Terme préférentiel
Sterol Regulatory Element Binding Protein 1
Type
-
mesh:Descriptor
Définition
- A sterol regulatory element binding protein that regulates expression of GENES involved in FATTY ACIDS metabolism and LIPOGENESIS. Two major isoforms of the protein exist due to ALTERNATIVE SPLICING. SREBP1-C is an isoform of sterol regulatory element binding protein 1 that is a weak activator of GENETIC TRANSCRIPTION. It is the predominant form in LIVER and ADIPOCYTES, and it mediates INSULIN induced FATTY ACIDS synthesis. SREBP1-A is an isoform of sterol regulatory element binding protein 1 that is a potent activator of GENETIC TRANSCRIPTION. It is the predominant form in SPLEEN.
Concept générique
Synonyme(s)
- SRE-1 Binding Protein
- SREBP1 Protein
- Sterol Regulatory Element-Binding Protein 1
Qualificatif(s) autorisé(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- agonists (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- biosynthesis (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- deficiency (Qualifier)
- drug effects (Qualifier)
- economics (Qualifier)
- genetics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- physiology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- ultrastructure (Qualifier)
- urine (Qualifier)
Traductions
-
français
-
Facteur de transcription SREBP-1
-
Facteur de transcription SREBP1
-
Facteur SREBP-1
-
Facteur transcriptionnel SREBP-1
-
Facteur transcriptionnel SREBP1
-
Protéine SREBP-1
-
Protéine SREBP1
-
Protéine-1 de fixation à l'élément de régulation des stérols
-
Protéine-1 se fixant à l'élément de régulation des stérols
-
Protéine-1 se liant à l'élément de régulation des stérols
URI
http://data.loterre.fr/ark:/67375/JVR-MQ11VK15-M
{{label}}
{{#each values }} {{! loop through ConceptPropertyValue objects }}
{{#if prefLabel }}
{{/if}}
{{/each}}
{{#if notation }}{{ notation }} {{/if}}{{ prefLabel }}
{{#ifDifferentLabelLang lang }} ({{ lang }}){{/ifDifferentLabelLang}}
{{#if vocabName }}
{{ vocabName }}
{{/if}}