Passer au contenu principal

Medical Subject Headings (thesaurus)

Choisissez le vocabulaire dans lequel chercher

aligner
annoter
télécharger

Concept information

Amino Acids, Peptides, and Proteins > Proteins > Nerve Tissue Proteins > Dysbindin
Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Vesicular Transport Proteins > Dysbindin
Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Dystrophin-Associated Proteins > Dysbindin
... > Amino Acids, Peptides, and Proteins > Proteins > Contractile Proteins > Muscle Proteins > Dystrophin-Associated Proteins > Dysbindin
Amino Acids, Peptides, and Proteins > Proteins > Cytoskeletal Proteins > Dystrophin-Associated Proteins > Dysbindin

Terme préférentiel

Dysbindin  

Type

  • mesh:Descriptor

Définition

  • A dystrophin-associated protein and component of the Biogenesis of Lysosomal Organelles Complex-1 (BLOC-1 complex) which is essential for the formation of LYSOSOME - derived organelles such as platelet dense granules and MELANOSOMES. DTNBP1 is expressed primarily in the brain and neurons, where it functions with ADAPTOR PROTEIN COMPLEX 3 to transport membrane proteins to NEURITES and nerve terminals. It also regulates the release of neurotransmitters, transport of synaptic vesicles, and localization of DOPAMINE D2 RECEPTORS. Mutations in the DTNBP1 gene are associated with Type 7 HERMANSKY-PUDLAK SYNDROME and SCHIZOPHRENIA.

Concept générique

Synonyme(s)

  • DTNBP1 Protein
  • Dysbindin-1
  • Dystrobrevin Binding Protein 1
  • Hermansky-Pudlak Syndrome 7 Protein

Qualificatif(s) autorisé(s)

Traductions

  • Dysbindine

    français

  • Dysbindine-1
  • Protéine DTNBP1
  • Protéine du syndrome de Hermansky-Pudlak de type 7
  • Protéine-1 de liaison à la dystrobrévine
  • Protéine-1 fixant la dystrobrévine
  • Protéine-1 liant la dystrobrévine

URI

http://data.loterre.fr/ark:/67375/JVR-MSFJL6S7-B

Télécharger ce concept :

RDF/XML TURTLE JSON-LD Date de création 11/07/2017, dernière modification le 05/04/2017