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Concept information

Cells > Cells, Cultured > Spheroids, Cellular

Terme préférentiel

Spheroids, Cellular  

Type

  • mesh:Descriptor

Définition

  • Spherical, heterogeneous aggregates of proliferating, quiescent, and necrotic cells in culture that retain three-dimensional architecture and tissue-specific functions. The ability to form spheroids is a characteristic trait of CULTURED TUMOR CELLS derived from solid TUMORS. Cells from normal tissues can also form spheroids. They represent an in-vitro model for studies of the biology of both normal and malignant cells. (From Bjerkvig, Spheroid Culture in Cancer Research, 1992, p4)

Concept générique

Synonyme(s)

  • Multicellular Spheroids

Traductions

URI

http://data.loterre.fr/ark:/67375/JVR-MV01PJ81-B

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RDF/XML TURTLE JSON-LD Date de création 27/12/1994, dernière modification le 09/07/2003