Concept information
Terme préférentiel
Phenytoin
Type
-
mesh:Descriptor
Définition
- An anticonvulsant that is used to treat a wide variety of seizures. It is also an anti-arrhythmic and a muscle relaxant. The mechanism of therapeutic action is not clear, although several cellular actions have been described including effects on ion channels, active transport, and general membrane stabilization. The mechanism of its muscle relaxant effect appears to involve a reduction in the sensitivity of muscle spindles to stretch. Phenytoin has been proposed for several other therapeutic uses, but its use has been limited by its many adverse effects and interactions with other drugs.
Concept générique
Synonyme(s)
- 2,4-Imidazolidinedione, 5,5-diphenyl-
- 4182431BJH
- 5,5-Diphenylhydantoin
- 5,5-diphenylimidazolidine-2,4-dione
- 57-41-0 (Phenytoin)
- 6158TKW0C5
- Diphenylhydantoin
- Fenitoin
Qualificatif(s) autorisé(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- agonists (Qualifier)
- analogs & derivatives (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- economics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- urine (Qualifier)
Action(s) pharmacologique(s)
Traductions
-
français
-
2,4-Imidazolidinedione, 5,5-diphenyl-
-
4182431BJH
-
57-41-0 (Phenytoin)
-
6158TKW0C5
URI
http://data.loterre.fr/ark:/67375/JVR-NRK4Q4CH-G
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