Passer au contenu principal

Medical Subject Headings (thesaurus)

Choisissez le vocabulaire dans lequel chercher

aligner
annoter
télécharger

Concept information

Biological Factors > Blood Coagulation Factors > Factor XII
Amino Acids, Peptides, and Proteins > Proteins > Blood Proteins > Blood Coagulation Factors > Factor XII
Amino Acids, Peptides, and Proteins > Proteins > Protein Precursors > Enzyme Precursors > Factor XII
Enzymes and Coenzymes > Enzyme Precursors > Factor XII

Terme préférentiel

Factor XII  

Type

  • mesh:Descriptor

Définition

  • Stable blood coagulation factor activated by contact with the subendothelial surface of an injured vessel. Along with prekallikrein, it serves as the contact factor that initiates the intrinsic pathway of blood coagulation. Kallikrein activates factor XII to XIIa. Deficiency of factor XII, also called the Hageman trait, leads to increased incidence of thromboembolic disease. Mutations in the gene for factor XII that appear to increase factor XII amidolytic activity are associated with HEREDITARY ANGIOEDEMA TYPE III.

Concept générique

Concepts spécifiques

Concepts associés

Synonyme(s)

  • 9001-30-3
  • Blood-coagulation factor XII
  • Coagulation Factor XII
  • Factor 12
  • Factor Twelve
  • Hageman Factor

Qualificatif(s) autorisé(s)

Traductions

  • Facteur XII

    français

  • 9001-30-3
  • Blood-coagulation factor XII
  • Facteur de Hageman
  • Facteur Hageman
  • Facteur XII de la coagulation
  • Facteur XII de la coagulation sanguine

URI

http://data.loterre.fr/ark:/67375/JVR-P6Z58324-4

Télécharger ce concept :

RDF/XML TURTLE JSON-LD Date de création 01/01/1999, dernière modification le 30/05/2019