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Concept information

Terme préférentiel

Granulins  

Type

  • mesh:Descriptor

Définition

  • Small, cysteine-rich peptides generated by the proteolytic cleavage of progranulin. Granulin peptides are each composed of a granulin-motif, while paragranulin is composed of a half-granulin motif. The mammalian granulins are named granulin 1-7 for their sequence order in the progranulin propeptide, and are alternately named granulin G, F, B, A, C, D, and E; or epithelin 7, 6, 2, 1, 3, 4, and 5, i.e. granulin 1 aka granulin G aka epithelin 7, etc. Granulin from the fifth granulin repeat of the proteolytically processed mammalian progranulin protein. It is also called granulin C or epithelin 3. Granulin from the seventh granulin repeat of the proteolytically processed mammalian progranulin protein. It is also called granulin E or epithelin 5. Granulin from the sixth granulin repeat of the proteolytically processed mammalian progranulin protein. It is also called granulin D or epithelin 4. Granulin from the fourth granulin repeat of the proteolytically processed mammalian progranulin protein. It is also called granulin A or epithelin 1. Granulin from the first granulin repeat of the proteolytically processed mammalian progranulin protein . It is also called Granulin G. Granulin from the second granulin repeat of the proteolytically processed mammalian progranulin protein. It is also called granulin F. Granulin from the third granulin repeat of the proteolytically processed mammalian progranulin protein . It is also called Granulin B. A granulin composed of the half granulin repeat.

Concept générique

Synonyme(s)

  • 148708-92-3
  • Epithelin
  • Epithelins
  • Granulin
  • Granulin Peptides

Traductions

  • français

  • 148708-92-3
  • Épithélines
  • Peptides de granuline

URI

http://data.loterre.fr/ark:/67375/JVR-PD7S7VH5-L

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RDF/XML TURTLE JSON-LD Date de création 09/07/2018, dernière modification le 27/05/2020