Concept information
Terme préférentiel
Granulins
Type
-
mesh:Descriptor
Définition
- Small, cysteine-rich peptides generated by the proteolytic cleavage of progranulin. Granulin peptides are each composed of a granulin-motif, while paragranulin is composed of a half-granulin motif. The mammalian granulins are named granulin 1-7 for their sequence order in the progranulin propeptide, and are alternately named granulin G, F, B, A, C, D, and E; or epithelin 7, 6, 2, 1, 3, 4, and 5, i.e. granulin 1 aka granulin G aka epithelin 7, etc. Granulin from the fifth granulin repeat of the proteolytically processed mammalian progranulin protein. It is also called granulin C or epithelin 3. Granulin from the seventh granulin repeat of the proteolytically processed mammalian progranulin protein. It is also called granulin E or epithelin 5. Granulin from the sixth granulin repeat of the proteolytically processed mammalian progranulin protein. It is also called granulin D or epithelin 4. Granulin from the fourth granulin repeat of the proteolytically processed mammalian progranulin protein. It is also called granulin A or epithelin 1. Granulin from the first granulin repeat of the proteolytically processed mammalian progranulin protein . It is also called Granulin G. Granulin from the second granulin repeat of the proteolytically processed mammalian progranulin protein. It is also called granulin F. Granulin from the third granulin repeat of the proteolytically processed mammalian progranulin protein . It is also called Granulin B. A granulin composed of the half granulin repeat.
Concept générique
Synonyme(s)
- 148708-92-3
- Epithelin
- Epithelins
- Granulin
- Granulin Peptides
Qualificatif(s) autorisé(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- agonists (Qualifier)
- analogs & derivatives (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- biosynthesis (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- deficiency (Qualifier)
- economics (Qualifier)
- genetics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- physiology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- urine (Qualifier)
Traductions
-
français
-
148708-92-3
-
Épithélines
-
Peptides de granuline
URI
http://data.loterre.fr/ark:/67375/JVR-PD7S7VH5-L
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