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Concept information

... > Enzymes and Coenzymes > Enzymes > Hydrolases > Peptide Hydrolases > Serine Proteases > Serine Endopeptidases > Factor XIIa
... > Enzymes and Coenzymes > Enzymes > Hydrolases > Peptide Hydrolases > Endopeptidases > Serine Endopeptidases > Factor XIIa
Biological Factors > Blood Coagulation Factors > Factor XII > Factor XIIa
... > Amino Acids, Peptides, and Proteins > Proteins > Blood Proteins > Blood Coagulation Factors > Factor XII > Factor XIIa
... > Amino Acids, Peptides, and Proteins > Proteins > Protein Precursors > Enzyme Precursors > Factor XII > Factor XIIa
Enzymes and Coenzymes > Enzyme Precursors > Factor XII > Factor XIIa

Terme préférentiel

Factor XIIa  

Type

  • mesh:Descriptor

Définition

  • Activated form of factor XII. In the initial event in the intrinsic pathway of blood coagulation, kallikrein (with cofactor HIGH MOLECULAR WEIGHT KININOGEN) cleaves factor XII to XIIa. Factor XIIa is then further cleaved by kallikrein, plasmin, and trypsin to yield smaller factor XII fragments (Hageman-Factor fragments). These fragments increase the activity of prekallikrein to kallikrein but decrease the procoagulant activity of factor XII.

Concept générique

Concepts associés

Synonyme(s)

  • Activated Factor XII
  • Blood Coagulation Factor XII, Activated
  • Coagulation Factor XIIa
  • Factor 12A
  • Factor Twelve A
  • Factor XII, Activated
  • Prekallikrein Activator

Qualificatif(s) autorisé(s)

Traductions

  • Facteur XIIa

    français

  • Facteur de Hageman activé
  • Facteur Hageman activé
  • Facteur XII activé
  • Facteur XIIa de la coagulation
  • Facteur XIIa de la coagulation sanguine

URI

http://data.loterre.fr/ark:/67375/JVR-PMKD9L6P-C

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RDF/XML TURTLE JSON-LD Date de création 25/05/1989, dernière modification le 30/05/2019