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Concept information

... > Amino Acids, Peptides, and Proteins > Peptides > Intracellular Signaling Peptides and Proteins > Adaptor Proteins, Signal Transducing > Shc Signaling Adaptor Proteins > Src Homology 2 Domain-Containing, Transforming Protein 1
... > Amino Acids, Peptides, and Proteins > Proteins > Intracellular Signaling Peptides and Proteins > Adaptor Proteins, Signal Transducing > Shc Signaling Adaptor Proteins > Src Homology 2 Domain-Containing, Transforming Protein 1
... > Amino Acids, Peptides, and Proteins > Proteins > Carrier Proteins > Adaptor Proteins, Signal Transducing > Shc Signaling Adaptor Proteins > Src Homology 2 Domain-Containing, Transforming Protein 1

Terme préférentiel

Src Homology 2 Domain-Containing, Transforming Protein 1  

Type

  • mesh:Descriptor

Définition

  • An SHC-signaling adaptor protein that transduces PHOSPHOTYROSINE-dependent signals downstream of RECEPTOR PROTEIN-TYROSINE KINASES and non-receptor tyrosine kinases. It is required for TGF-BETA-induced CELL MIGRATION; NEOLPASM INVASION; and METASTASIS of BREAST NEOPLASMS; its SH2 DOMAIN is essential for tumor survival. It also functions in signaling downstream of ANGIOPOIETIN RECEPTOR TIE-2, regulating the migration of ENDOTHELIAL CELLS; and PHYSIOLOGIC NEOVASCULARIZATION.

Concept générique

Synonyme(s)

  • SHC1 Protein
  • SHC1 (Src Homology 2 Domain-Containing) Protein
  • ShcA Protein
  • SHC (Src Homology 2 Domain-Containing) Transforming Protein 1
  • SHC-Transforming Protein 1
  • Src Homology 2 Domain-Containing-Transforming Protein C1

Qualificatif(s) autorisé(s)

Traductions

  • Protéine transformante-1 contenant un domaine d'homologie-2 de Src

    français

  • Protéine SHC1
  • Protéine SHC1 (contenant un domaine d'homologie-2 de Src)
  • Protéine ShcA
  • Protéine transformante C1 contenant un domaine d'homologie-2 de Src
  • Protéine transformante SHC1
  • Protéine transformante-1 contenant un domaine d'homologie de type 2 avec Src
  • Protéine transformante-1 SHC
  • Protéine transformante-1 SHC (contenant un domaine d'homologie-2 de Src)

URI

http://data.loterre.fr/ark:/67375/JVR-PS467ZK8-K

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RDF/XML TURTLE JSON-LD Date de création 08/07/2016, dernière modification le 15/04/2016