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Concept information

Terme préférentiel

Neuritis, Autoimmune, Experimental  

Type

  • mesh:Descriptor

Définition

  • An experimental animal model for the demyelinating disease of GUILLAINE-BARRE SYNDROME. In the most frequently used protocol, animals are injected with a peripheral nerve tissue protein homogenate. After approximately 2 weeks the animals develop a neuropathy secondary to a T cell-mediated autoimmune response directed towards the MYELIN P2 PROTEIN in peripheral nerves. Pathologic findings include a perivascular accumulation of macrophages and T lymphocytes in the peripheral nervous system, similar to that seen in the Guillaine-Barre syndrome. (From Adams et al., Principles of Neurology, 6th ed, p1314; J Neuroimmunol 1998 Apr 1;84(1):40-52)

Synonyme(s)

  • Allergic Neuritis, Experimental
  • Autoimmune Neuritis, Experimental
  • EAN (Experimental Allergic Neuritis)
  • EAN (Experimental Autoimmune Neuritis)
  • Experimental Allergic Neuritis
  • Experimental Autoimmune Neuritis
  • Experimental Autoimmune Neuropathy
  • Neuritis, Experimental Allergic
  • Neuritis, Experimental Autoimmune

Traductions

  • français

  • Neuropathie auto-immune expérimentale
  • Neuropathie autoimmune expérimentale
  • Névrite allergique expérimentale
  • Névrite autoimmune expérimentale
  • Névrite expérimentale allergique

URI

http://data.loterre.fr/ark:/67375/JVR-PT3F9904-R

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RDF/XML TURTLE JSON-LD Date de création 23/02/1981, dernière modification le 05/07/2019