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Concept information

... > Enzymes and Coenzymes > Enzymes > Oxidoreductases > Oxygenases > Mixed Function Oxygenases > Cytochrome P-450 Enzyme System > Steroid Hydroxylases > Sterol 14-Demethylase
... > Amino Acids, Peptides, and Proteins > Proteins > Hemeproteins > Cytochromes > Cytochrome P-450 Enzyme System > Steroid Hydroxylases > Sterol 14-Demethylase
Enzymes and Coenzymes > Cytochromes > Cytochrome P-450 Enzyme System > Steroid Hydroxylases > Sterol 14-Demethylase
... > Enzymes and Coenzymes > Enzymes > Oxidoreductases > Oxygenases > Mixed Function Oxygenases > Cytochrome P-450 Enzyme System > Cytochrome P450 Family 51 > Sterol 14-Demethylase
... > Amino Acids, Peptides, and Proteins > Proteins > Hemeproteins > Cytochromes > Cytochrome P-450 Enzyme System > Cytochrome P450 Family 51 > Sterol 14-Demethylase
Enzymes and Coenzymes > Cytochromes > Cytochrome P-450 Enzyme System > Cytochrome P450 Family 51 > Sterol 14-Demethylase

Terme préférentiel

Sterol 14-Demethylase  

Type

  • mesh:Descriptor

Définition

  • An NADPH-dependent P450 enzyme that plays an essential role in the sterol biosynthetic pathway by catalyzing the demethylation of 14-methyl sterols such as lanosterol. The enzyme acts via the repeated hydroxylation of the 14-methyl group, resulting in its stepwise conversion into an alcohol, an aldehyde and then a carboxylate, which is removed as formic acid. Sterol 14-demethylase is an unusual cytochrome P450 enzyme in that it is found in a broad variety of organisms including ANIMALS; PLANTS; FUNGI; and protozoa.

Concept générique

Synonyme(s)

  • CYP51 Cytochrome P-450
  • Cytochrome P-450 CYP51
  • Eburicol 14 alpha-Demethylase
  • Eburicol 14alpha-Demethylase
  • Lanosterol 14 alpha-Demethylase
  • Obtusifoliol 14alpha-Demethylase
  • Sterol 14-alpha-Demethylase
  • Sterol 14-Demethylases

Qualificatif(s) autorisé(s)

Traductions

  • Sterol 14-demethylase

    français

  • Cytochrome P-450 CYP51
  • Eburicol 14 alpha-demethylase
  • Éburicol 14 alpha-déméthylase
  • Lanosterol 14 alpha-demethylase
  • Obtusifoliol 14alpha-demethylase
  • Sterol 14-alpha-demethylase
  • Stérol 14-alpha-déméthylase
  • Stérol 14-déméthylase

URI

http://data.loterre.fr/ark:/67375/JVR-PTLF6NKZ-L

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RDF/XML TURTLE JSON-LD Date de création 25/06/2010, dernière modification le 05/07/2019