Concept information
Terme préférentiel
Aromatase
Type
-
mesh:Descriptor
Définition
- An enzyme that catalyzes the desaturation (aromatization) of the ring A of C19 androgens and converts them to C18 estrogens. In this process, the 19-methyl is removed. This enzyme is membrane-bound, located in the endoplasmic reticulum of estrogen-producing cells of ovaries, placenta, testes, adipose, and brain tissues. Aromatase is encoded by the CYP19 gene, and functions in complex with NADPH-FERRIHEMOPROTEIN REDUCTASE in the cytochrome P-450 system.
Concept générique
Synonyme(s)
- Androstenedione Aromatase
- CYP 19
- CYP19
- CYP19 Protein
- Cytochrome P450 19
- Cytochrome P-450(AROM)
- Cytochrome P-450 CYP19
- Estrogen Synthase
- Estrogen Synthetase
- P450AROM
Qualificatif(s) autorisé(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- analysis (Qualifier)
- biosynthesis (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- deficiency (Qualifier)
- drug effects (Qualifier)
- economics (Qualifier)
- genetics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- physiology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- ultrastructure (Qualifier)
- urine (Qualifier)
Traductions
-
français
-
CYP 19
-
CYP19
-
Cytochrome P-450 CYP19
-
Cytochrome P450 19
-
Cytochrome P450arom
URI
http://data.loterre.fr/ark:/67375/JVR-PX8X8NRK-B
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