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Concept information

Endocrine System Diseases > Gonadal Disorders > Ovarian Diseases > Primary Ovarian Insufficiency
... > Urogenital Diseases > Female Urogenital Diseases and Pregnancy Complications > Female Urogenital Diseases > Genital Diseases, Female > Adnexal Diseases > Ovarian Diseases > Primary Ovarian Insufficiency
... > Urogenital Diseases > Genital Diseases > Genital Diseases, Female > Adnexal Diseases > Ovarian Diseases > Primary Ovarian Insufficiency

Terme préférentiel

Primary Ovarian Insufficiency  

Type

  • mesh:Descriptor

Définition

  • Cessation of ovarian function after MENARCHE but before the age of 40, without or with OVARIAN FOLLICLE depletion. It is characterized by the presence of OLIGOMENORRHEA or AMENORRHEA, elevated GONADOTROPINS, and low ESTRADIOL levels. It is a state of female HYPERGONADOTROPIC HYPOGONADISM. Etiologies include genetic defects, autoimmune processes, chemotherapy, radiation, and infections. The most commonly known genetic cause is the expansion of a CGG repeat to 55 to 199 copies in the 5' untranslated region in the X-linked FMR1 gene. A form of ovarian failure, caused by resistance to GONADOTROPINS stimulation. It may be caused by defects in the receptors for FOLLICLE STIMULATING HORMONE or LUTEINIZING HORMONE. It may be due to factors interfering with the actions of gonadotropins, such as antibodies blocking the ligand-receptor interaction.

Concept générique

Concepts associés

Synonyme(s)

  • Ovarian Failure, Premature
  • Premature Ovarian Failure

Qualificatif(s) autorisé(s)

Traductions

  • Insuffisance ovarienne primitive

    français

  • Défaillance ovarienne précoce
  • Défaillance ovarienne prématurée
  • Insuffisance ovarienne précoce
  • Insuffisance ovarienne prématurée
  • Insuffisance ovarienne primaire
  • IOP (Insuffisance Ovarienne Prématurée)
  • IOP (Insuffisance Ovarienne Primitive)

URI

http://data.loterre.fr/ark:/67375/JVR-QHV8D3Q6-Q

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RDF/XML TURTLE JSON-LD Date de création 30/05/1991, dernière modification le 30/06/2021