Concept information
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Peptides
Intracellular Signaling Peptides and Proteins
Protein-Tyrosine Kinases
src-Family Kinases
Terme préférentiel
Lymphocyte Specific Protein Tyrosine Kinase p56(lck)
Type
-
mesh:Descriptor
Définition
- This enzyme is a lymphoid-specific src family tyrosine kinase that is critical for T-cell development and activation. Lck is associated with the cytoplasmic domains of CD4, CD8 and the beta-chain of the IL-2 receptor, and is thought to be involved in the earliest steps of TCR-mediated T-cell activation.
Concept générique
Synonyme(s)
- lck Kinase
- p56 lck
- Protein Tyrosine Kinase p56(lck)
- Proto-Oncogene Protein c-lck
- Proto-Oncogene Protein lck
Qualificatif(s) autorisé(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- biosynthesis (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- deficiency (Qualifier)
- drug effects (Qualifier)
- economics (Qualifier)
- genetics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- physiology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- ultrastructure (Qualifier)
- urine (Qualifier)
Traductions
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français
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Kinase lck
-
p56(lck)
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Protéine p56(lck)
-
Protéine proto-oncogène c-lck
-
Protéine proto-oncogène lck
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Protéine tyrosine kinase p56(lck)
URI
http://data.loterre.fr/ark:/67375/JVR-QM1454N5-8
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