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Concept information

Terme préférentiel

MPTP Poisoning  

Type

  • mesh:Descriptor

Définition

  • A condition caused by the neurotoxin MPTP which causes selective destruction of nigrostriatal dopaminergic neurons. Clinical features include irreversible parkinsonian signs including rigidity and bradykinesia (PARKINSON DISEASE, SECONDARY). MPTP toxicity is also used as an animal model for the study of PARKINSON DISEASE. (Adams et al., Principles of Neurology, 6th ed, p1072; Neurology 1986 Feb;36(2):250-8)

Synonyme(s)

  • MPTP-Induced Parkinsonism
  • MPTP Neurotoxicity Syndrome
  • Neurotoxicity Syndrome, MPTP
  • Poisoning, 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine

Traductions

  • français

  • Intoxication due au 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
  • Neurotoxicité induite par le MPTP
  • Parkinsonisme dû au MPTP

URI

http://data.loterre.fr/ark:/67375/JVR-QNQ8NHC2-R

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RDF/XML TURTLE JSON-LD Date de création 08/11/1999, dernière modification le 25/06/2010