Concept information
Terme préférentiel
Nomifensine
Type
-
mesh:Descriptor
Définition
- An isoquinoline derivative that prevents dopamine reuptake into synaptosomes. The maleate was formerly used in the treatment of depression. It was withdrawn worldwide in 1986 due to the risk of acute hemolytic anemia with intravascular hemolysis resulting from its use. In some cases, renal failure also developed. (From Martindale, The Extra Pharmacopoeia, 30th ed, p266)
Concept générique
Synonyme(s)
- 1LGS5JRP31
- 24526-64-5 (Nomifensine)
- 32795-47-4 (maleate (1:1))
- 76S8CUH5MR
- 8-Isoquinolinamine, 1,2,3,4-tetrahydro-2-methyl-4-phenyl-
- Linamiphen
- Nomifensin
Qualificatif(s) autorisé(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- agonists (Qualifier)
- analogs & derivatives (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- economics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- urine (Qualifier)
Action(s) pharmacologique(s)
Traductions
-
français
-
1LGS5JRP31
-
24526-64-5 (Nomifensine)
-
32795-47-4 (maleate (1:1))
-
76S8CUH5MR
-
8-Isoquinolinamine, 1,2,3,4-tetrahydro-2-methyl-4-phenyl-
URI
http://data.loterre.fr/ark:/67375/JVR-QV54589P-M
{{label}}
{{#each values }} {{! loop through ConceptPropertyValue objects }}
{{#if prefLabel }}
{{/if}}
{{/each}}
{{#if notation }}{{ notation }} {{/if}}{{ prefLabel }}
{{#ifDifferentLabelLang lang }} ({{ lang }}){{/ifDifferentLabelLang}}
{{#if vocabName }}
{{ vocabName }}
{{/if}}