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Concept information

Terme préférentiel

tau Proteins  

Type

  • mesh:Descriptor

Définition

  • Microtubule-associated proteins that are mainly expressed in neurons. Tau proteins constitute several isoforms and play an important role in the assembly of tubulin monomers into microtubules and in maintaining the cytoskeleton and axonal transport. Aggregation of specific sets of tau proteins in filamentous inclusions is the common feature of intraneuronal and glial fibrillar lesions (NEUROFIBRILLARY TANGLES; NEUROPIL THREADS) in numerous neurodegenerative disorders (ALZHEIMER DISEASE; TAUOPATHIES).

Synonyme(s)

  • tau Protein

Traductions

URI

http://data.loterre.fr/ark:/67375/JVR-R096N43X-R

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RDF/XML TURTLE JSON-LD Date de création 12/07/1991, dernière modification le 05/07/2016