Concept information
...
Glycoproteins
Membrane Glycoproteins
ATP-Binding Cassette Transporters
ATP Binding Cassette Transporter, Subfamily B
...
Glycoproteins
Membrane Glycoproteins
ATP-Binding Cassette Transporters
ATP Binding Cassette Transporter, Subfamily B
...
Membrane Proteins
Membrane Glycoproteins
ATP-Binding Cassette Transporters
ATP Binding Cassette Transporter, Subfamily B
...
Membrane Proteins
Membrane Transport Proteins
ATP-Binding Cassette Transporters
ATP Binding Cassette Transporter, Subfamily B
...
Carrier Proteins
Membrane Transport Proteins
ATP-Binding Cassette Transporters
ATP Binding Cassette Transporter, Subfamily B
Terme préférentiel
ATP Binding Cassette Transporter, Subfamily B, Member 1
Type
-
mesh:Descriptor
Définition
- A 170-kDa transmembrane glycoprotein from the superfamily of ATP-BINDING CASSETTE TRANSPORTERS. It serves as an ATP-dependent efflux pump for a variety of chemicals, including many ANTINEOPLASTIC AGENTS. Overexpression of this glycoprotein is associated with multidrug resistance (see DRUG RESISTANCE, MULTIPLE).
Concept générique
Synonyme(s)
- ABCB1 Protein
- ATP-Binding Cassette, Sub-Family B, Member 1
- ATP Binding Cassette Transporter, Sub-Family B, Member 1
- CD243 Antigen
- MDR1 Protein
- Multidrug Resistance Protein 1
- P-Glycoprotein
- PGY-1 Protein
Qualificatif(s) autorisé(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- agonists (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- biosynthesis (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- deficiency (Qualifier)
- drug effects (Qualifier)
- economics (Qualifier)
- genetics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- physiology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- ultrastructure (Qualifier)
- urine (Qualifier)
Traductions
-
français
-
P-gp
-
Protéine MDR1
URI
http://data.loterre.fr/ark:/67375/JVR-RDNJDZPW-L
{{label}}
{{#each values }} {{! loop through ConceptPropertyValue objects }}
{{#if prefLabel }}
{{/if}}
{{/each}}
{{#if notation }}{{ notation }} {{/if}}{{ prefLabel }}
{{#ifDifferentLabelLang lang }} ({{ lang }}){{/ifDifferentLabelLang}}
{{#if vocabName }}
{{ vocabName }}
{{/if}}