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Concept information

Terme préférentiel

ATP Binding Cassette Transporter, Subfamily B, Member 1  

Type

  • mesh:Descriptor

Définition

  • A 170-kDa transmembrane glycoprotein from the superfamily of ATP-BINDING CASSETTE TRANSPORTERS. It serves as an ATP-dependent efflux pump for a variety of chemicals, including many ANTINEOPLASTIC AGENTS. Overexpression of this glycoprotein is associated with multidrug resistance (see DRUG RESISTANCE, MULTIPLE).

Synonyme(s)

  • ABCB1 Protein
  • ATP-Binding Cassette, Sub-Family B, Member 1
  • ATP Binding Cassette Transporter, Sub-Family B, Member 1
  • CD243 Antigen
  • MDR1 Protein
  • Multidrug Resistance Protein 1
  • P-Glycoprotein
  • PGY-1 Protein

Traductions

URI

http://data.loterre.fr/ark:/67375/JVR-RDNJDZPW-L

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RDF/XML TURTLE JSON-LD Date de création 20/07/1998, dernière modification le 13/07/2018