Concept information
Terme préférentiel
Integrin alpha2beta1
Type
-
mesh:Descriptor
Définition
- An integrin found on fibroblasts, platelets, endothelial and epithelial cells, and lymphocytes where it functions as a receptor for COLLAGEN and LAMININ. Although originally referred to as the collagen receptor, it is one of several receptors for collagen. Ligand binding to integrin alpha2beta1 triggers a cascade of intracellular signaling, including activation of p38 MAP kinase.
Concept générique
Synonyme(s)
- alpha2beta1Integrin
- CD49b-CD29
- Glycoprotein Ia-IIa
- Platelet Membrane Glycoprotein Heterodimer Ia-IIa
- Very Late Antigen-2
- VLA-2
Qualificatif(s) autorisé(s)
- administration & dosage (Qualifier)
- agonists (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- biosynthesis (Qualifier)
- blood (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- deficiency (Qualifier)
- drug effects (Qualifier)
- genetics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- physiology (Qualifier)
- radiation effects (Qualifier)
- therapeutic use (Qualifier)
- ultrastructure (Qualifier)
Traductions
-
français
-
Antigène-2 de l'activation très tardive
-
CD49b-CD29
-
Intégrine alpha-2-bêta-1
-
Intégrine alpha2 bêta1
-
VLA-2
URI
http://data.loterre.fr/ark:/67375/JVR-RZR9MB17-G
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