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Concept information

Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Receptors, Cell Surface > Receptors, Death Domain

Terme préférentiel

Receptors, Death Domain  

Type

  • mesh:Descriptor

Définition

  • A family of cell surface receptors that signal via a conserved domain that extends into the cell CYTOPLASM. The conserved domain is referred to as a DEATH DOMAIN due to the fact that many of these receptors are involved in APOPTOSIS signaling pathways. Several DEATH DOMAIN RECEPTOR SIGNALING ADAPTOR PROTEINS can bind to the death domains of the activated receptors and through a complex series of interactions activate apoptotic mediators such as CASPASES.

Concept générique

Concepts spécifiques

Concepts associés

Synonyme(s)

  • Death Domain Receptors
  • Death Receptor
  • Death Receptors
  • Receptors, Death Domain Family
  • Receptors, DR Family

Qualificatif(s) autorisé(s)

Traductions

URI

http://data.loterre.fr/ark:/67375/JVR-S331W3FM-M

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RDF/XML TURTLE JSON-LD Date de création 05/07/2006, dernière modification le 27/05/2020