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Concept information

Terme préférentiel

Shwartzman Phenomenon  

Type

  • mesh:Descriptor

Définition

  • Hemorrhagic necrosis that was first demonstrated in rabbits with a two-step reaction, an initial local (intradermal) or general (intravenous) injection of a priming endotoxin (ENDOTOXINS) followed by a second intravenous endotoxin injection (provoking agent) 24 h later. The acute inflammation damages the small blood vessels. The following intravascular coagulation leads to capillary and venous THROMBOSIS and NECROSIS. Shwartzman phenomenon can also occur in other species with a single injection of a provoking agent, and during infections or pregnancy. Its susceptibility depends on the status of IMMUNE SYSTEM, coagulation, FIBRINOLYSIS, and blood flow.

Synonyme(s)

  • Schwartzman Phenomenon
  • Schwartzman Reaction
  • Shwartzman Reaction

Traductions

URI

http://data.loterre.fr/ark:/67375/JVR-S66PW2GV-P

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RDF/XML TURTLE JSON-LD Date de création 01/01/1999, dernière modification le 25/06/2010