Concept information
Terme préférentiel
Cytochrome P-450 CYP2B1
Type
-
mesh:Descriptor
Définition
- A major cytochrome P-450 enzyme which is inducible by PHENOBARBITAL in both the LIVER and SMALL INTESTINE. It is active in the metabolism of compounds like pentoxyresorufin, TESTOSTERONE, and ANDROSTENEDIONE. This enzyme, encoded by CYP2B1 gene, also mediates the activation of CYCLOPHOSPHAMIDE and IFOSFAMIDE to MUTAGENS.
Concept générique
Synonyme(s)
- 7-Benzyloxyresorufin O-Dealkylase
- 7-Pentylresorufin O-Depentylase
- Benzyloxyresorufin O-Dealkylase
- BROD
- CYP 2B1
- CYP2B1
- Cytochrome P450 2B1
- Pentoxyresorufin O-Dealkylase
- PROD
Qualificatif(s) autorisé(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- biosynthesis (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- deficiency (Qualifier)
- drug effects (Qualifier)
- economics (Qualifier)
- genetics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- physiology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- ultrastructure (Qualifier)
- urine (Qualifier)
Traductions
-
français
-
Benzyloxyrésorufine O-désalkylase
-
BROD
-
CYP 2B1
-
CYP2B1
-
Cytochrome P450 2B1
-
Pentoxyrésorufine O-désalkylase
-
PROD
URI
http://data.loterre.fr/ark:/67375/JVR-S817MB3N-K
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