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Concept information

Chemical Actions and Uses > Pharmacologic Actions > Molecular Mechanisms of Pharmacological Action > Enzyme Inhibitors > Gamma Secretase Inhibitors and Modulators

Terme préférentiel

Gamma Secretase Inhibitors and Modulators  

Type

  • mesh:Descriptor

Définition

  • Agents that suppress GAMMA-SECRETASE by inhibiting or modulating its activities. Targeted enzymatic activities include its involvement in accumulation of toxic AMYLOID BETA-PEPTIDES (e.g., Aβ42) in ALZHEIMER DISEASE and activation of NOTCH RECEPTOR mediated SIGNAL PATHWAYS in certain cancer types.

Concept générique

Synonyme(s)

  • GS Inhibitors and Modulators

Qualificatif(s) autorisé(s)

Traductions

URI

http://data.loterre.fr/ark:/67375/JVR-S92Z2NV5-6

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RDF/XML TURTLE JSON-LD Date de création 09/07/2021, dernière modification le 30/06/2021